Prevalence of iron deficiency and iron deficiency anemia in patients with hemophilia
- VernacularTitle:Гемофилтэй өвчтөнүүдийн дунд төмөр дутагдал ба төмөр дутагдлын цус багадалтын илрэлийг судалсан дүн
- Author:
Narangerel B
1
;
Ankhbayar D
1
;
Munkhuu A
1
;
Burenbayar Ch
1
;
Odgerel Ts
2
,
3
,
4
Author Information
1. Department of Internal Medicine, Postgraduate Training Institute, MNUMS
2. Mongolian&ndash
3. Japanese Hospital, MNUMS
4. Department of Hematology, School of Medicine, MNUMS
- Publication Type:Journal Article
- Keywords:
Hemorrhage;
Coagulation factor deficiency;
Bleeding disorder
- From:
Mongolian Journal of Health Sciences
2025;86(2):42-45
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Iron deficiency (ID) and iron deficiency anemia (IDA) are among the most common forms of anemia
worldwide. Although the underlying causes of ID may vary depending on a country’s developmental level, lifestyle, and
other factors, blood loss remains the principal cause leading to ID and subsequent IDA. In hemophilia, recurrent bleeding
due to deficiencies of coagulation factors (FVIII, FIX, FXI) can lead to ID, which may progress to IDA and adversely
affect the quality of life in these patients. The absence of studies evaluating the prevalence of ID and IDA among hemophiliac
patients in Mongolia provided the impetus for this investigation.
Aim:To assess the prevalence of ID and IDA among patients with hemophilia.
Materials and Methods:A cross-sectional study was conducted among 45 patients with hemophilia registered at the Hemophilia
Comprehensive Center (HCC), Mongolia-Japan Hospital, Mongolian National University of Medical Sciences.
All participants underwent laboratory testing, including complete blood count (CBC) and serum ferritin levels—were
performed using the SYSMEX XN2000 and COBAS BM6010 analyzers. Data analysis was carried out using SPSS 27.0
and MS Excel 2010.
Results:Among the 45 cases, 41 were Hemophilia A and 4 were Hemophilia B. Reduced serum iron levels were found in
33.3% (15), and low ferritin levels were observed in 22.2%. Detailed blood tests revealed microcytic hypochromic changes
in 43.9% (18) of Hemophilia A cases and in 100% (4) of Hemophilia B cases. The overall prevalence of ID was 13.3%,
while the prevalence of IDA was 22.2%. Among the IDA cases, 90.0% were classified as mild and 10.0% as moderate.
Notably, 80.0% of the IDA cases occurred in children under 15 years of age.
Conclusion:ID and IDA are common among hemophiliac patients. The high prevalence among children under 15 years
of age suggests an age-related predisposition, emphasizing the need to improve disease management and to implement
preventive measures against anemia in this population.
- Full text:202505271317265212442-45.pdf
