Comparative study of subcutaneous fat area and visceral fat area among healthy and metabolic syndrome patients
- VernacularTitle:Бодисын солилцооны хамшинжтэй хүмүүсийн гадар өөхөн эдийн талбай болон дотор өөхөн эдийн талбайг эрүүл хүмүүстэй харьцуулан судлах нь
- Author:
Munkh-Erdene U
1
;
Odmaa T
1
;
Solongo Ts
1
;
Ganchimeg S
1
;
Egshiglen G
1
;
Anir B
2
;
Ariunaa A
2
;
Navchaa G
2
;
Tulgaa S
1
;
Munkhtsetseg J
1
Author Information
1. Department of Biochemistry, School of Biomedicine, MNUMS
2. NURA Ai Health screening center
- Publication Type:Journal Article
- Keywords:
Obesity;
Cardiovascular disease;
Lipid metabolism
- From:
Mongolian Journal of Health Sciences
2025;86(2):36-41
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Obesity, especially central obesity, is a risk factor for non-communicable chronic diseases such as dyslipidemia,
type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), and metabolic syndrome (MetS).
Aim:Study the association between the subcutaneous fat area (SFA) and visceral fat area (VFA) with lipid metabolism
parameters in adults with MetS.
Materials and Methods:Data from 1511 participants who visited the ‘NURA Mongolia’ Ai Health screening center
between September 2023 and February 2024, including general information, DEXA (Dual X-ray Absorptiometry), and
biochemical analysis results, were used. Metabolic syndrome (MeS) was assessed based on the harmonizing criteria 2009
(≥3 criteria). VFA and SFA were categorized into four groups using quartiles (Q1-Q4). Statistical analysis was performed
using SPSS v26, including T-tests, multiple logistic regression (OR, 95% CI), and ROC (AUC) analysis.
Results:The average age of the participants was 30.5±3.9 years, with a BMI of 25.1 kg/m², and 49.5% were male. The
group with MetS (n=531) had significantly higher levels of VFA and SFA compared to the group that rated their health as
relatively healthy and had no clinical diagnosis (n=979) (control group) (p<0.0001), with males showing higher VFA and
females showing higher SFA (p<0.0001). The Q4 group for VFA had a significant association with MetS in males (4.611,
95% CI=2.394–9.591) and females (2.253, 95% CI=1.097-3.912) (p<0.001). Logistic regression analysis showed that increased
VFA was more strongly associated with MetS in males (β=0.325, p<0.0001) and females (β=0.338, p<0.003) than
BMI. The AUC for predicting MetS was 0.790 (95% CI=0.750-0.831) for VFA and 0.401 (95% CI=0.351-0.451) for SFA,
with all results being statistically significant (p<0.001). VFA had a higher predictive value compared to other markers.
Conclusion:In healthy men with metabolic syndrome, VFA is more prominently defined, while SFA is higher in healthy
women. Since VFA is a better predictor of metabolic syndrome than SFA, it increases the risk of diseases such as cardiovascular
diseases and type 2 diabetes in men, whereas SFA in women serves as a protective factor.
- Full text:202505271311425032436-41.pdf
