Standardization study of flower of Trollius asiaticus L.
- VernacularTitle:Азийн жамьянмядаг (Тrollius asiaticus L.) ургамлын цэцгийн стандартчиллын судалгаа
- Author:
Bayarkhuu Ts
1
;
Davaadavga D
1
;
Daariimaa KH
1
Author Information
1. Department of Pharmaceutical chemistry and Pharmacognosy, School of Pharmacy, MNUMS
- Publication Type:Journal Article
- Keywords:
Orientin;
Gallic acid;
High performance liquid chromatography;
Total flavoinods;
Total phenoliс
- From:
Mongolian Journal of Health Sciences
2025;85(1):6-9
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Globally, researchers have found that while the use of synthetic drugs worldwide has increased by 2.1
2.5%, the use of natural medicines has grown by 3.5-4.8%. In modern times, the pharmaceutical industry has become
more advanced, and the use of plant-based medicines is increasing. As a result, there is a growing need to identify
biologically active compounds in medicinal plants and produce domestic pharmaceutical products to replace imported
medicines. Due to the limited research on evaluating the quality of the raw materials of the Asian globeflower(Тrollius
asiaticus L.) this study serves as a basis for assessing the quality of that flowers
Aim:Determining the quality parameters of flower of Trollius asiaticus L.
Materials and Methods:The research work was carried out with the support of the “Quality Control Laboratory for
Medicine” of the School of Pharmacy, MNUMS. The quality assessment of flower of Trollius asiaticus L. was conducted
according to established parameters outlined in the National Pharmacopoeia of Mongolia and Russian pharmacopeia and
Chinese pharmacopeia methods. Parameters such as appearance, and microbiological purity were evaluated. Statistical
analysis of research data was performed using Microsoft Excel and SPSS 25 software to calculate the mean, standard
deviation, and percentage.
Results:The flower of Trollius asiaticus L. is orange red or orange, plant does not contain organic and mineral impurities,
the quality analysis of flavonoid compounds by the thin layer chromatography, a spot with RF=0.5125 was detected at
the same level as orientin as a standard substance, and a spot with RF=0.875 was detected at the same level as gallic acid
as a standard substance when analyzing the quality of polyphenolic compounds, moisture contain is 5.52%, sulfated ash
contain is 9.12%, acid insoluble ash contain is 3.39%, water soluble extract contained 36.21%, the total polyphenolic
compound contained 5.37±0.22%, total flavonoid compound contained 0.0399±0.013%.
Conclusion:The quality parameters of flower of Trollius asiaticus L. have been determined by the Mongolia National of
Pharmacopoeia, the Pharmacopoeia of Russian and China.
- Full text:20250527124112698276-9.pdf
