Research and application progress on recognition components of surface plasmon resonance sensors in the pharmaceutical field
10.12206/j.issn.2097-2024.202309014
- VernacularTitle:表面等离子共振传感器的识别元件在医药领域中的研究应用进展
- Author:
Xiaofei WANG
1
;
Ying ZHANG
1
;
Jiayu GU
2
,
3
;
Xiner HU
2
,
4
;
Hai ZHANG
4
;
Yan CAO
1
Author Information
1. School of Pharmacy, Naval Medical University, Shanghai 200433, China.
2. School of Pharmacy, Naval Medical University, Shanghai 200433, China
3. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
4. The Maternal and Infant Health Hospital Affiliated to Tongji University, Shanghai 200040, China.
- Publication Type:Reviews
- Keywords:
surface plasmon resonance;
recognition element;
antibodies;
aptamers;
molecularly imprinted polymer
- From:
Journal of Pharmaceutical Practice and Service
2025;43(5):205-212
- CountryChina
- Language:Chinese
-
Abstract:
Surface plasmon resonance （SPR） sensor is an optical detection technique enables real-time and dynamic monitoring of biological samples. SPR-based biosensors have remarkable characteristics such as label-free detection and high sensitivity, making them important tools for studying molecular interactions. The recognition element, which plays a critical role in SPR sensors,which could specifically identify and capture of target analytes, closely influencing the selectivity performance of the sensor. The progress on SPR sensors in pharmaceutical research were reviewed, which focused on the application of recognition elements such as antibodies, aptamers, molecularly imprinted polymers, and metal nanoparticles.
