Dynamic Sequential Diagnosis and Treatment of Pediatric Nephrotic Syndrome Based on the "Sweat Pore-Qi and Liquid-Kidney Collaterals"
10.13288/j.11-2166/r.2025.10.006
- VernacularTitle:基于“玄府-气液-肾络”探讨儿童肾病综合征动态序贯辨治思路
- Author:
Zhenhua YUAN
1
;
Mingyang CAI
1
;
Yingying JIANG
1
;
Jingjing WU
1
;
Wenqing PAN
1
;
Zichao DING
1
;
Shuzi ZHANG
1
;
Xianqing REN
1
Author Information
1. Pediatrics Department，The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou，450000
- Publication Type:Journal Article
- Keywords:
nephrotic syndrome;
sweat pore;
qi and liquid;
kidney collaterals;
sequential therapy;
children
- From:
Journal of Traditional Chinese Medicine
2025;66(10):1007-1010
- CountryChina
- Language:Chinese
-
Abstract:
Based on the viewpoint of "sweat pore-qi and liquid-kidney collaterals"， it is believed that children's nephrotic syndrome is caused by the core mechanism of sweat pore constraint and closure， qi and liquid imbalance， and kidney collaterals impairment， and it is proposed that the treatment principle is to nourish the sweat pore， regulate qi and fluid， and supplement the kidney and unblock the collaterals. In clinic， guided by sequential therapy and according to the different disease mechanism characteristics of the four stages， including early stage of the disease， hormone induction stage， hormone reduction stage， hormone maintenance stage， the staged dynamic identification and treatment was applied. For early stage of the disease with edema due to yang deficiency， modified Zhenwu Decoction （真武汤） was applied to warm yang and drain water； for hormone induction stage with yin deficiency resulting in effulgent fire， modified Zhibai Dihuang Pill （知柏地黄丸） plus Erzhi Pill （二至丸） was used to enrich yin and reduce fire； for hormone reduction stage with qi and yin deficiency， modified Shenqi Dihuang Decoction （参芪地黄汤） was used to boost qi and nourish yin； for hormone maintenance stage， modified Shenqi Pill （肾气丸） was used to supplement yin and yang. Meanwhile， the treatment also attaches importance to the combination of vine-based or worm medicinals to dredge collaterals， so as to providing ideas for clinical treatment.
