Academic connotation of the "three phases and three methods" theory in preventing and treating radiation-induced lung injury
10.3969/j.issn.1006-2157.2025.03.015
- VernacularTitle:“三期三法”防治放射性肺损伤的学术内涵
- Author:
Kangdi CAO
1
;
Dandan WANG
1
;
Shuaihang HU
1
;
Jiawei WANG
1
;
Wei HOU
1
Author Information
1. Guang anmen Hospital, China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
radiation-induced lung injury;
three phases and three methods;
blazing heat toxin phase;
yin deficiency and heat accumulation phase;
static blood obstruction phase
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(3):412-417
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced lung injury is a prevalent side effect of radiotherapy for chest cancer. The "three phases and three methods "is an innovative theory based on the evolution of the core pathogenesis of radiation-induced lung injury. Its formation also considers the understanding of radiation-induced lung injury by ancient and modern medical practitioners, pathological characteristics, clinical manifestations, and the development patterns of radiation-induced lung injury. The "three phases and three methods" refers to the three phases of the course and the three treatment methods. The core pathogenesis of radiation-induced lung injury from the beginning, middle and late stages is heat toxicity, yin deficiency, and blood stasis. Therefore, the course of radiation-induced lung injury is divided into three phases: blazing heat toxin, yin deficiency and heat accumulation, and static blood obstruction. The method of clearing the lung and resolving toxins, enriching yin and venting heat, invigorating blood and dissolving stasis are used respectively. Traditional Chinese medicines commonly used in each phase include Flos Lonicerae, Atrina Glass, heartleaf houttuynia herb, Radix Ophiopogonis, American Ginseng, Forsythiae Fructus, Radix Salviae Miltiorrhizae, Rhizoma Ligustici chuanxiong, Scorpio, etc. This article presents the theoretical origins of the "three phases and three methods" concept by reviewing of ancient literature, inheriting experience, and summarizing disease pathogenesis, as well as elaborating on the academic connotations of the "three phases and three methods". The scientific validity of the "three phases and three methods" is verified by literature, clinical, and basic research. The "three phases and three methods" interprets the core characteristics of each stage of radiation-induced lung injury, improves the traditional Chinese medicine prevention and treatment system for radiation-induced lung injury, and provides theoretical basis for achieving complete process management.
- Full text:2025052209420335510Academic connotation of the _three phases and three methods_ theory in preventing and treating radiation-induced lung injury.pdf
