Visceral Fat Thickness Predicts Fatty Liver in Koreans with Type 2 Diabetes Mellitus.
10.3346/jkms.2008.23.2.256
- Author:
Hai Jin KIM
1
;
Min Ho CHO
;
Jong Suk PARK
;
Ji Sun NAM
;
Eun Seok KANG
;
Chul Woo AHN
;
Bong Soo CHA
;
Eun Jig LEE
;
Sung Kil LIM
;
Kyung Rae KIM
;
Hyun Chul LEE
;
Kap Bum HUH
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Yongdong Severance Hospital, Seoul, Korea. acw@yumc.yonsei.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Visceral Fat Thickness;
Fatty Liver;
Type 2 Diabetes Mellitus
- MeSH:
Aged;
Aorta/pathology;
Cohort Studies;
Diabetes Complications/*diagnosis;
Diabetes Mellitus, Type 2/*diagnosis/pathology;
Fatty Liver/*complications/*diagnosis;
Female;
Humans;
Intra-Abdominal Fat/*pathology;
Male;
Middle Aged;
Models, Statistical;
Odds Ratio;
ROC Curve;
Sensitivity and Specificity
- From:Journal of Korean Medical Science
2008;23(2):256-261
- CountryRepublic of Korea
- Language:English
-
Abstract:
Our aim was to study whether visceral adiposity is a predictor of diabetic fatty liver in Korean type 2 diabetes mellitus. In this study, abdominal ultrasonography was used to assess the presence of fatty liver in 1,898 patients with type 2 diabetes. We measured visceral fat thickness by high-resolutional ultrasonography and insulin resistance by Kitt. Half of the cohort had a fatty liver (50.2%). High visceral fat thickness had the highest odds ratio for developing fatty liver in both sexes (odds ratio [S.D]: 3.14 [2.24-4.69], p<0.00 in male, 2.84 [2.04-3.93], p<0.00 in female). In addition, visceral fat thickness of 42.45 and 37.7 mm in men and women, respectively, were chosen as the discriminating value to predict the presence of fatty liver with a sensitivity of 71% and 73% and a specificity of 70% and 70% in men and women, respectively. The area under the receiver-operating characteristics curve was 0.759 in men and 0.764 in women. Therefore we could conclude that the degree of visceral adiposity predicts the presence of fatty liver type 2 diabetes mellitus, whether centrally obese or not, suggesting that hepatic fat accumulation in a diabetic fatty liver may be influenced by visceral fat accumulation regardless of waist circumference.
