Results of Using Mineral Spray in children 2-16 years of age with Atopic Dermatitis
- VernacularTitle: Атопийн арьсны үрэвсэлтэй 2-16 насны хүүхдүүдэд рашаан шүршлэг хэрэглэсэн үр дүн
- Author:
Minjinsuvd B
1
;
Enkhtur Ya
1
;
Dugarmaa U
1
Author Information
1. Department of Dermatology, School of Medicine, MNUMS
- Publication Type:Clinical Trial
- Keywords:
SCORAD;
VAS;
SCH;
TEWL;
Shargaljuut mineral spray
- From:
Mongolian Journal of Health Sciences
2025;88(4):42-46
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Atopic dermatitis (AD) is a common chronic and relapsing inflammatory skin disease in young children,
clinically characterized by pruritus and skin rashes. Epidemiological studies have reported that AD affects 5–30% of
children and 1-10% of adults worldwide. In recent years, the use of mineral waters for the treatment of chronic skin con
ditions has become increasingly popular globally. Although mineral waters, particularly from Shargaljuut springs, have
been traditionally used in Mongolia for various dermatological conditions, no studies have been conducted on their use in
atopic dermatitis, providing the rationale for this study
Aim:To evaluate the result of Shargaljuut mineral spray on disease severity, pruritus intensity, and selected physiological
parameters of the skin in children with atopic dermatitis.
Materials and Methods:This clinical trial study with a placebo-controlled group included children aged 2-16 years with
AD. The participants were treated with Shargaljuut spray and the clinical assessment was conducted before and after the
treatment, evaluating severity using SCORAD (Severity Scoring of Atopic Dermatitis), itching intensity using VAS (Vi
sual Analog Scale), skin hydration (SCH) and transepidermal water loss (TEWL).
Results:Among all participants, 81.7% (n=49) had mild atopic dermatitis based on SCORAD scores, and 18.3% (n=11)
had moderate severity. According to the VAS scores, 40% (n=24) of the participants reported mild pruritus. Skin hydration
was found to be severely decreased in 96.7% (n=58) of the cases, while TEWL values were within normal limits in 76.7%
(n=46). Statistically significant differences were observed between the experimental and control groups at day 30 in terms
of disease severity and pruritus intensity, as well as in certain skin physiological parameters (p=0.001, p=0.002). Within
the experimental group, statistically significant differences were also detected in disease severity (p=0.001), pruritus
intensity (p=0.002), skin hydration (p=0.002), and TEWL (p=0.001) between baseline, day 15, and day 30. A correlation
was found between transepidermal water loss (TEWL) and skin hydration (r=0.566, p=0.0001).
Conclusions:1. Among the children with atopic dermatitis (AD) included in the study, 81.7% (n=49) had a mild severity score
according to SCORAD, 40% (n=24) had mild itching intensity based on the VAS assessment, 96.7% (n=58) had
excessively dry skin, and 76.7% (n=46) showed good transepidermal water loss (TEWL) levels.
2. In the experimental group, comparisons of disease severity, itching intensity, skin hydration, and TEWL levels be
fore and after the use of the Shargaljuut spring water spray revealed that skin hydration increased, TEWL decreased,
and both disease severity and itching intensity were reduced following treatment
- Full text:202505201807367929242-46.pdf
