Theoretical and methodological issues in human ecogenetics
- VernacularTitle:Хүний экогенетикийн онол, арга зүйн асуудалд
- Author:
Bolortuya N
1
;
Otgonjargal D
1
Author Information
1. Medical School of Branch of Darkhan, MNUMS
- Publication Type:Journal Article
- Keywords:
environment;
adaptation;
mutagen;
genetic code
- From:
Diagnosis
2024;110(3):19-24
- CountryMongolia
- Language:Mongolian
-
Abstract:
Human ecogenetics is a broad area of research. It is prioritized in terms of necessity and, in general, is a branch of medicine that studies the unique characteristics of each individual's genetic makeup, adaptation, and response to mutagens.
Approximately 25,000 polymorphic systems are responsible for enzymes, receptors, and elements of human molecular biochemistry. Enzyme systems, transport systems, transport proteins, antigens, and so many variants of receptors cause each individual to respond differently to the effects of chemical metabolism, and physical, and biological factors. The unique characteristics of each individual are the study of human ecogenetics.
Today, elucidating the chemical and physical factors that affect the health of millions of people around the world, and recognizing the interaction between mutagens and the human body, has become the basic direction of scientific research on the one hand, and the main principle of personalized medicine on the other hand.
Ecogenetic research is widely used to solve many theoretical and practical problems. 5% of all newborns in the world are born with congenital malformations. About 30% of all newborn deaths are related to congenital malformations or genetic disorders. Various unfavorable factors of the human ecosystem affect human health, and as this effect is constantly increasing, eco-pathological studies in the field of medicine have been intensively conducted. In recent years scientists, the study of the biological basis of the environment and human interaction based on the integrated ecological-physiological method, including the ecological evaluation and importance of physical, social and technical factors, the study of their combined and separate effects, the structure of human ecogenetic links , the elucidation of individual response characteristics is in full swing.
- Full text:2025052013194360962Diagnosis-2024-110(3)-19-24.pdf
