History, Experience, Opportunities, and Challenges in Esophageal Cancer Prevention and Treatment in Linxian, Henan Province, A High Incidence Area for Esophageal Cancer
10.3971/j.issn.1000-8578.2025.24.1329
- VernacularTitle:河南省林县食管癌高发现场防治传承研究的历史、经验、机遇和挑战
- Author:
Lidong WANG
1
;
Xiaoqian ZHANG
2
,
3
;
Xin SONG
1
;
Xueke ZHAO
1
;
Duo YOU
1
;
Lingling LEI
1
;
Ruihua XU
1
;
Jin HUANG
1
;
Wenli HAN
1
;
Ran WANG
1
;
Qide BAO
4
;
Aifang JI
5
;
Lei MA
6
;
Shegan GAO
7
Author Information
1. Henan Key Laboratory for Esophageal Cancer Research and National Key Laboratory of Metabolism Disorder and Esophageal Cancer Prevention & Treatment of the First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.
2. Henan Key Laboratory for Esophageal Cancer Research and National Key Laboratory of Metabolism Disorder and Esophageal Cancer Prevention & Treatment of the First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China
3. Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China.
4. Department of Oncology, Anyang District Hospital, Anyang 455000, China.
5. Department of Clinical Laboratory, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000, China.
6. Henan Provincial Key Laboratory of Tumor Molecular Biology Medicine, Nanyang First People's Hospital, Nanyang 473000, China.
7. Department of Oncology, the First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471003, China.
- Publication Type:ExpertForum
- Keywords:
Esophageal cancer;
Linxian experience;
Field-study on prevention and treatment;
High incidence area for esophageal cancer
- From:
Cancer Research on Prevention and Treatment
2025;52(4):251-255
- CountryChina
- Language:Chinese
-
Abstract:
Linxian County in Henan Province, Northern China is known as the region with the highest incidence and mortality rate of esophageal cancer worldwide. Since 1959, the Henan medical team has conducted field work on esophageal cancer prevention and treatment in Linxian. Through three generations of effort exerted by oncologists over 65 years of research on esophageal cancer prevention and treatment in Linxian, the incidence rate of esophageal squamous cell carcinoma in this area has dropped by nearly 50%, and the 5-year survival rate has increased to 40%, reaching the international leading level. This article aims to summarize the history, present opportunities and new challenges, and explore the experience of esophageal cancer prevention and treatment in Linxian (referred to as the “Linxian experience”), providing reference and guidance to cancer prevention and treatment research in China.
