Study of some bioactive substances contained in dry extracts of cultivated Inula helenium L. plant
- VernacularTitle:Тарималжуулсан өндөр зоосон цэцэг (Inula helenium .L) ургамлын хуурай ханданд агуулагдах зарим биологийн идэвхт бодисын судалгаа
- Author:
Bujinlkham B
1
,
2
;
Sugarmaa B
1
;
Batdorj D
1
;
Ganchimeg G
1
;
Saikhanbayar P
1
;
Munkhzaya B
1
;
Maral L
1
;
Badamtsetseg S
1
;
Lkhaasuren R
1
;
Akhtolkhyn T
2
Author Information
1. Drug Research Institute
2. Mongolian University of Pharmaceutical Sciences
- Publication Type:Journal Article
- From:
Mongolian Pharmacy and Pharmacology
2024;25(2):29-37
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction: Since 1993, the Inula helenium L. plant has been planted in the production area (Bulgan
Province, Dashinchilen Sum) of the Traditional Hatchery Science and Production Corporation’s medicinal
plant introduction and cultivation experience. At the Drug Research Institute, there is also a botanical institute
for medicinal plants where it is grown. In traditional Mongolian medicine, the roots and rhizomes of Inula
helenium L. are used to reduce inflammation, boost immunity, enhance hunger, and improve intestinal
motility. Inula helenium L. roots and rhizomes contain biologically active compounds such as monoterpenes,
sesquiterpenes, phenols, flavonoids, and polysaccharides.
Methods: The roots and rhizomes of Inula helenium L. were extracted with water and 70% ethanol at the
following ratios 1:10 (2% of WAC), 1:8, and 1:6 by partial maceration at 700C for 2 hours each, extracted
and concentrated. The dry extract was obtained by the spray drying procedure. High-performance liquid
chromatography for determining the content of alantolactone, thin-layer chromatography for qualitative
analysis. Spectrophotometer for determining the content of polyphenolic compounds, colored compounds
with Folin-Ciocalteu reagent for qualitative analysis. Spectrophotometer for determining the content of inulin, and colored compounds with phenol and sulfuric acid solutions for qualitative analysis.
Conclusion: In determining the content of polyphenolic compounds, inulin, and alantolactone in the dry extract
taken from the roots and rhizomes of cultivated Inula helenium L., the content of polyphenolic compound in dry extract A was 2.50±0.08%, and alantolactone was 1.39±0.11% in the raw material of the plant, while B dry the extract had a high concentration of inulin of 58.51±0.66%.
- Full text:2025051102495225224MPPJ-2024-25(2)-29-37.pdf
