Review of medicinal plant decontamination methods to ensure microbiological aspects
- VernacularTitle:Ургамлын гаралтай бүтээгдэхүүний микробиологийн цэвэршилтийг хангах аргуудын талаарх хэвлэлийн тойм өгүүлэл
- Author:
Munkhzaya B
1
;
Saikhanbayar P
1
;
Maral L
1
;
Maralgua A
1
;
Bujinlkham B
1
;
Lkhaasuren R
1
;
Akhsholpan B
1
Author Information
1. Drug Research Institute
- Publication Type:Journal Article
- Keywords:
herbal preparation;
sterilization;
decontamination;
dry extract
- From:
Mongolian Pharmacy and Pharmacology
2024;24(1):72-79
- CountryMongolia
- Language:Mongolian
-
Abstract:
The incorporation of botanical elements such as Inula helenium L., Astragalus mongolicus Bge.,
Iris tenuifolia Pall., Ribes diacanthum Pall., and Oxytropis pseudoglandulosa Grubov plays a pivotal role in the formulation of immune-enhancing and kidney-protective Mongolian traditional medicines. These herbal constituents bear rich historical significance in traditional remedies. Ensuring the purity of these herbs is a vital stride in the production of efficacious supplements and medications. Thus, meticulous decontamination of microorganisms assumes paramount importance. The selection of an appropriate sterilization method is important for manufacturers. Sterilization methods divide within three main categories: thermal, chemical, and radiation. This spectrum encompasses many techniques, ranging from moist heat and dry heat to gamma irradiation, ethylene oxide, ozone, and UV treatment. This comprehensive review discusses the efficacy of gamma irradiation, dry heat, moist heat, and chemical treatments, presenting a comparative analysis of their merits. Practically, heat sterilization emerges as a simple and cost-efficient choice. The utilization of an autoclave, subjecting powdered spice paprika to temperatures between 108-125°C for 120 seconds, yielded a substantial reduction in microbial load without compromising the integral bioactive compounds. Gamma
irradiation, a common practice in the healthcare and pharmaceutical sectors, stands as another choice in the area of sterilization techniques. Beyond sterilization, upholding rigorous standards of sanitation and hygiene remains a key in the preparations of medicinal plants.
- Full text:2025051102032531021MPPJ-2024-24(1)-72-79.pdf
