Incompatibility of drug excipients: A review
- VernacularTitle:Эмийн туслах бодисын үл нийцлийн талаарх тойм судалгаа
- Author:
Maral L
1
;
Maralgua A
1
;
Munkhzaya B
1
;
Bujinlkham B
1
;
Saikhanbayar P
1
;
Lkhaasuren R
1
;
Akhsholpan B
1
Author Information
1. Drug Research Institute
- Publication Type:Review
- From:
Mongolian Pharmacy and Pharmacology
2024;24(1):68-71
- CountryMongolia
- Language:Mongolian
-
Abstract:
Excipients are important in the composition of drugs and are the most important requirements for maintaining
the stability of drug form, dosage, and physicochemical parameters. Excipients act as protective agents,
bulking agents and can also be used to improve bioavailability of drugs in some instances Auxiliary
substances included in the composition of medicines are classified as natural, animal, synthetic and
semisynthetic. Excipients can become inactive due to chemical, microbiological and physiological effects.
Commonly used pharmaceutical excipients are fillers, stabilizers, preservatives, flavor and aroma modifiers,
binders, disintegrants, lubricants, lubricants, solvents, and coating agents. Excipients can be considered as
indispensible component of medicinal products and in most of the formulations they are present in greater
proportion with regards to active pharmaceutical ingredient, as it forms the bulk of the formulation it is
always necessary to select an excipient which satisfies the ideal properties for a particular excipient. In this
review, materials about coating agents widely used in pharmaceutical practice were compiled from electronic
databases such as Pubmed, Google Scholar, and other scientific web pages, using keywords such as Drug
excipient interaction, Stability in Oral Solid, and Excipient. .
- Full text:2025051101594914776MPPJ-2024-24(1)-68-71.pdf
