To determine the effect of fish bile-2 oil application on burn
- VernacularTitle:Түлэнхийн шарханд үзүүлэх загасны цөс -2 тосон түрхцийн үйлдлийг тогтоох нь
- Author:
Pagamdulam A
1
;
Altantuya Ts
1
;
Bold Sh
1
Author Information
1. Mongolian University of Pharmaceutical Sciences
- Publication Type:Journal Article
- Keywords:
fish bile;
red ochre;
burnt
- From:
Mongolian Pharmacy and Pharmacology
2024;24(1):44-49
- CountryMongolia
- Language:Mongolian
-
Abstract:
In our country, burnt occupies a high percentage among the unexpected injuries depending on the living
conditions.
Children and adults who have recovered after treatment in the burn unit may need further treatment, such
as surgery to release the burn scar especially, on the movable joint of the body. It requires a lot of money.
Therefore, in order to accelerate healing and solve their economic difficulties, ingredients that have been
used in traditional medicine but have been proven to be effective in the past century and not used in the field of health today, should be selected from ancient medical scriptures and books and confirmed by clinical trials and introduced into the clinic. I have chosen this topic for research work.
Research materials and methodology: The experimental research work was carried out based on the laboratory of the Institute of Traditional Medicine Technology and the standard methodology of modern pharmaceutical science, and according to the standard methodology of pharmacology, 2.5*2.0*2.5cm sized burn wounds were administered to white Wistar rats weighing 180-200g.
On days 0, 7, 14, 21, and 28 after the formation of the pathological model, and histological analysis of the
wound healing area was performed, and the healing rate of the wound area was evaluated by mathematical calculations, and the process was confirmed by photographs.
Result: By planimetry, the size of the burn wound was reduced by 2 times in the X1 treatment group compared to the control group on the 28th day. According to the results of histological analysis, inflammatory cells and hyper proliferation of fibroblast cells in the dermis layer of the rats in the untreated control group were reduced, and the bundles of collagen fibers were relatively orderly.
Conclusion: According to the size of the wound healing area and the histological analysis results, it was found in our research that among the tested groups, the inflammatory, granulation, and regeneration stages of the wound healing in the Version 1 group were relatively active or in a short time, and they regenerated the skin tissue.
- Full text:2025051101394418192MPPJ-2024-24(1)-44-49.pdf
