Meniere’s disease: an inner ear disease caused by multiple factors
10.12025/j.issn.1008-6358.2025.20250369
- VernacularTitle:梅尼埃病：多因素交互导致的内耳疾病
- Author:
Huaili JIANG
1
,
2
;
Xinsheng HUANG
1
,
2
Author Information
1. Department of Otolaryngology Head and Neck Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
2. Vertigo Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
- Publication Type:Monographicreport:Multi-disciplinarydiagnosisandtreatmentofvertigo
- Keywords:
Meniere’s disease;
endolymphatic hydrops;
immune mechanism;
genetic factor;
multifactorial interaction
- From:
Chinese Journal of Clinical Medicine
2025;32(2):161-164
- CountryChina
- Language:Chinese
-
Abstract:
Meniere’s disease (MD) is an inner ear disorder characterized by recurrent vertigo, fluctuating hearing loss, tinnitus, and aural fullness. The pathogenesis of MD remains unclear but is closely associated with endolymphatic hydrops (EH), immune dysregulation, genetic predisposition, vascular dysfunction, and viral infection. This review summarizes recent research advances of MD pathogenesis, suggesting that MD may be a heterogeneous condition with distinct subtypes driven by different mechanisms. Future studies should integrate multi-omics analyses and animal models to elucidate its molecular pathways.
