The mechanism of effective traditional Chinese medicine components and prescriptions in treatment of chronic pancreatitis by intervening against pancreatic stellate cells
- VernacularTitle:中药有效成分及方剂干预胰腺星状细胞治疗慢性胰腺炎的作用机制
- Author:
Ruyang CHENG
1
;
Weining SONG
1
;
Xin JIANG
1
;
Yehao WANG
1
;
Lin LIU
1
;
Fang LU
2
;
Shumin LIU
2
Author Information
- Publication Type:Review
- Keywords: Pancreatitis， Chronic; Traditional Chinese Drugs; Pancreatic Stellate Cells
- From: Journal of Clinical Hepatology 2025;41(4):793-800
- CountryChina
- Language:Chinese
- Abstract: Chronic pancreatitis （CP） is a chronic disease characterized by recurrent inflammation and progressive damage to pancreatic tissue， and its deterioration may increase the risk of pancreatic cancer in patients with CP， which seriously threatens the health of patients with CP. In recent years， studies on the pathogenesis of CP have mostly focused on the activation of pancreatic stellate cells （PSCs） and its role in pancreatic fibrosis. This article elaborates on the mechanism of action of PSCs in CP， summarizes the current status of research on effective traditional Chinese medicine components and prescriptions for intervention of PSCs in the treatment of chronic CP， and proposes the future research directions for effective traditional Chinese medicine components and prescriptions， so as to provide a reference for the clinical treatment of CP patients in the future.
