The role of gut microbiota in acute kidney injury in patients with decompensated liver cirrhosis and related targeted therapies
- VernacularTitle:肠道菌群在失代偿期肝硬化并发急性肾损伤中的致病机制及相关靶向治疗
- Author:
Qingbiao LIN
1
;
Guiqiang WANG
1
Author Information
- Publication Type:Review
- Keywords: Liver Cirrhosis; Acute Kidney Injury; Gastrointestinal Microbiome; Therapeutics
- From: Journal of Clinical Hepatology 2025;41(4):773-777
- CountryChina
- Language:Chinese
- Abstract: Acute kidney injury （AKI） is a severe complication in patients with decompensated liver cirrhosis and tends to have a high mortality rate and a poor prognosis. Current studies have shown that gut microbiota might be associated with the development and progression of AKI， and it is necessary to pay attention to the application of targeted therapy based on gut microbiota in the prevention and treatment of such patients. Therefore， this article reviews the possible pathogenesis of gut microbiota in liver cirrhosis comorbid with AKI， as well as potential prevention and treatment measures targeting gut microbiota， in order to provide a reference for the pathogenesis of such patients and related treatment methods.
