Association between sarcopenia and abnormal lipid metabolism in patients with liver cirrhosis and the potential benefits of transjugular intrahepatic portosystemic shunt
- VernacularTitle:肝硬化患者肌少症与脂质代谢异常的关系及经颈静脉肝内门体分流术干预的潜在益处
- Author:
Qinnian LI
1
;
Bilian ZHU
1
;
Yingmei TANG
1
;
Chenrui ZHANG
1
Author Information
- Publication Type:Review
- Keywords: Liver Cirrhosis; Sarcopenia; Lipid Metabolism Disorders; Portasystemic Shunt， Transjugular Intrahepatic
- From: Journal of Clinical Hepatology 2025;41(4):768-772
- CountryChina
- Language:Chinese
- Abstract: With the progression of liver cirrhosis， patients often develop sarcopenia and lipid metabolism disorders， and the complex interaction between p sarcopenia and lipid metabolism disorders not only promotes the progression of liver cirrhosis， but also affects the prognosis and quality of life of patients. As an effective intervention for alleviating complications associated with liver cirrhosis， transjugular intrahepatic portosystemic shunt （TIPS） can improve sarcopenia to a certain degree by improving hepatic hemodynamics and reducing portal venous pressure. In addition， there might be varying degrees of changes in blood lipid levels after TIPS， which may be closely associated with the recovery of liver metabolic function and the alterations in hemodynamics. This article introduces the association between liver cirrhosis， sarcopenia， and lipid metabolism disorders， elaborates on the effect of TIPS on sarcopenia and abnormal lipid metabolism， and discusses related mechanism and clinical significance， in order to provide a theoretical basis for clinical treatment.
