Advances in the establishment and application of preclinical tumor models of pancreatic cancer
- VernacularTitle:胰腺癌临床前肿瘤模型的建立与应用进展
- Author:
Changwei DU
1
;
Yueze LIU
1
;
Zhe CAO
1
;
Taiping ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Pancreatic Neoplasms; Models， Biological; Patient-derived Xenografts; Conditionally Reprogrammed; Organoids
- From: Journal of Clinical Hepatology 2025;41(4):605-610
- CountryChina
- Language:Chinese
- Abstract: This article reviews the research advances in the characteristics and application progress of various new models for preclinical cancer research on pancreatic cancer， analyzes and discusses the history， current research status， and advantages and disadvantages of new models of pancreatic cancer， including patient-derived tissue xenograft， conditional reprogramming， and patient derived organoids， and it also reviews the studies that have achieved clinical transformation from preclinical models and proposes possible research prospects in the future.
