Trend analysis of birth defects in Fengxian District， Shanghai， 2018‒2022
10.19428/j.cnki.sjpm.2025.24288
- VernacularTitle:2018—2022年上海市奉贤区出生缺陷发病趋势分析
- Author:
Huihui MA
1
;
Hong CHEN
1
;
Hong JIANG
2
;
Guangsheng LIANG
3
;
Qin HUANG
4
;
Meng QIN
5
Author Information
1. Department of Maternal Health, Shanghai Fengxian Maternal and Child Health Hospital, Shanghai 201499, China
2. School of Public Health, Fudan University, Shanghai 200032, China
3. The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China
4. Shanghai Yangpu Maternal and Child Health Hospital (Center), Shanghai 200082, China
5. Shanghai Fengxian District Center for Disease Control and Prevention, Shanghai 201499, China
- Publication Type:Journal Article
- Keywords:
birth defect;
perinatal infant;
congenital heart disease;
surveillance;
trend analysis
- From:
Shanghai Journal of Preventive Medicine
2025;37(2):174-178
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo retrospectively analyze the epidemiological trends of birth defects in perinatal infants in Fengxian District, Shanghai from 2018 to 2022, so as to provide a scientific evidence for the formulation of related prevention and control strategies. MethodsBased on the data from the National Birth Defects Surveillance System, statistical analysis was conducted on the perinatal birth defects from monitored hospitals within the region from 2018 to 2022. ResultsFrom 2018 to 2022, a total of 20 870 perinatal infants delivered in the monitored hospitals in Fengxian District, with 472 cases with birth defects, showing a significant increase in the prevalence of birth defects (PRR=1.49, 95%CI: 1.39‒1.59). The risk of birth defects increased with maternal age, especially for advanced maternal age (PRR=1.58, 95%CI: 1.12‒2.25). Infants born to mothers with gestational diabetes had a higher prevalence of birth defects compared to those without gestational diabetes (PRR=1.99, 95%CI: 1.46‒2.70). Infants with birth defects were more likely to be born prematurely (PRR=2.07, 95%CI:1.56‒2.76). The top three types of birth defects were congenital heart disease (CHD), other anomalies of the external ear, and polydactyly. ConclusionThe prevalence of birth defects in Fengxian District monitored hospitals showed an upward trend from 2018 to 2022. Advanced maternal age and gestational diabetes were identified as risk factors for birth defects. CHD is the leading type of birth defect in Fengxian District over the five-year period. To reduce the prevalence of birth defects, it is crucial to implement comprehensive prevention and treatment measures for CHD.
