Correlation between CD4+T lymphocytes and viral load in newly identified human immunodeficiency virus infected individuals in Huangpu District，Shanghai，2023
10.19428/j.cnki.sjpm.2025.24323
- VernacularTitle:2023年上海市黄浦区新发现人类免疫缺陷病毒感染者CD4+T淋巴细胞和病毒载量相关性
- Author:
Shuang ZHU
1
;
Jieqiong ZHAN
1
;
Lili SONG
1
;
Yu WANG
1
;
Wei CHU
1
;
Weihua CHEN
1
;
Huimin XU
1
Author Information
1. Huangpu District Center for Disease Control and Prevention, Shanghai 200023, China
- Publication Type:Journal Article
- Keywords:
human immunodeficiency virus,HIV;
CD4+T lymphocyte;
virus load;
infection;
elderly
- From:
Shanghai Journal of Preventive Medicine
2025;37(2):125-128
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the detected results of CD4+T lymphocytes and viral load in newly identified human immunodeficiency virus (HIV) infected patients in Huangpu District of Shanghai in 2023, to explore the correlation between them, so as to provide a scientific basis for the development of targeted prevention and control measures and antiviral treatment programs. MethodsThe data of CD4 cell count, viral load and demographic characteristics of the newly infected patients living with HIV in Huangpu District, Shanghai in 2023 were collected and analyzed by using descriptive epidemiological method. ResultsThe mean CD4 cell count of the 67 newly identified HIV infected patients in Huangpu District was (301.22±235.19) cells·µL-1, with a mean viral load of (5.15±1.28) ×105 copies·mL-1.There were statistically significant differences in CD4 cell count and viral load among different age groups (P<0.05), but there were no statistically significant differences by gender and marital status (both P>0.05). The CD4 cell count and CD4/CD8 ratio both were negatively correlated with the lg value of viral load (r=-0.290, -0.378; P=0.027, 0.002). ConclusionThe CD4 cell counts of the newly identified HIV infected patients in Huangpu District in 2023 were generally low, the proportion of patients with high viral load was high, but the risk for elderly infected with HIV was high. The elderly have gradually become the key population for AIDS prevention and control in Huangpu District. It is recommended to expand HIV screening in the elderly to reduce the risk of HIV transmission and increase the rate of early detection and treatment.
