Advances in the diagnosis and treatment of ocular surface squamous neoplasia
10.3980/j.issn.1672-5123.2025.5.09
- VernacularTitle:眼表鳞状细胞肿瘤诊断及治疗新进展
- Author:
Wen GENG
1
;
Huatao XIE
1
;
Jiasong WANG
1
;
Mingchang ZHANG
1
Author Information
1. Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022,Hubei Province, China
- Publication Type:Journal Article
- Keywords:
ocular surface squamous neoplasia;
topical chemotherapy;
high-resolution optical coherence tomography
- From:
International Eye Science
2025;25(5):743-748
- CountryChina
- Language:Chinese
-
Abstract:
Ocular surface squamous neoplasia(OSSN)is a series of pathological solid tumors formed by dysplasia of keratoconjunctival epithelium, which is one of the most common ocular surface tumors in adults. In the past two decades, the treatment of OSSN has gradually changed from surgical resection to topical chemotherapy. Interferons, 5-fluorouracil and mitomycin are the most commonly used topical agents for the clinical treatment of this disease. This paper summarizes the diagnosis of OSSN and various local chemotherapy treatment options, highlights the potential role of high-resolution optical coherence tomography(HR-OCT)technology in the diagnosis and treatment of this disease.
