Current situation， ethical challenges， and key points of ethical review for non-human primate experiments
10.12026/j.issn.1001-8565.2025.04.08
- VernacularTitle:非人灵长类动物实验现状、伦理挑战及审查要点
- Author:
Qin HE
1
;
Youzhi DENG
2
;
Jiyin ZHOU
3
Author Information
1. Department of Scientific Research and Teaching， Chengdu Seventh People’s Hospital， Chengdu 610213， China
2. Clinical Research Center， West China Hospital， Sichuan University， Chengdu 610041， China
3. Clinical Medical Research Center， the Second Affiliated Hospital of Army Medical University， Chongqing 400037， China
- Publication Type:Journal Article
- Keywords:
non-human primate;
ethical challenge;
key points of ethical review
- From:
Chinese Medical Ethics
2025;38(4):455-461
- CountryChina
- Language:Chinese
-
Abstract:
Non-human primates are the closest relatives of human beings and possess similar morphological， anatomical， physiological， and behavioral characteristics， making them indispensable in fields such as neuroscience， reproduction， infectious diseases， and drug research and development. Currently， the restrictions on using non-human primates in experiments are becoming increasingly stringent in Europe and the United States. These experiments have ethical particularities that are different from those involving ordinary animals， and they also pose ethical challenges such as lack of necessity assessment， no unified assessment standards， and ethical dumping hazards. Supervision and ethical review should be strengthened. The key points of their ethical review include the necessity of the experiments， the assessment of the harm-benefit ratio， and the implementation of the “3R” principles.
