The Proposal of the Concept of "New Pathogen Invading the Collaterals" and Its Value
10.13288/j.11-2166/r.2025.08.003
- VernacularTitle:“新感入络”概念的提出及其临床应用价值
- Author:
Zhenhua JIA
1
Author Information
1. Hebei Yiling Hospital，Shijiazhuang，050091
- Publication Type:Journal Article
- Keywords:
new pathogen invading the collaterals;
new diseases;
new pathogen;
chronic diseases entering the colla-terals
- From:
Journal of Traditional Chinese Medicine
2025;66(8):775-779
- CountryChina
- Language:Chinese
-
Abstract:
In the Qing Dynasty， YE Gui proposed the pathogenesis of "chronic diseases entering the collaterals" as a rule for collateral diseases. In the context of viral respiratory diseases， the course of the disease is considered a relative concept. A systematic review of historical literature reveals that "new pathogens" belong to the category of "new diseases". It identifies that "new diseases" include types where the pathogenic qi initially invades without harming the righteous qi， where old diseases relapse while not being completely cured， and where chronic diseases suddenly flare up. These are not limited to exogenous diseases. "New pathogens" refer to diseases caused by the invasion of warm-heat pathogens， the six excesses， and epidemic qi， differing from the modern traditional Chinese medicine term "new warm diseases" related to latent heat diseases. Based on the "collaterals-meridians-collaterals" transformation pathway described in The Inner Canon of Yellow Emperor （《黄帝内经》） and the pathogenesis of external pathogens entering the zang-fu organs via the meridians as described in Treatise on Febrile Disease （《伤寒论》）， as well as the external warm diseases' transformation rule explained by YE Gui from the perspective of collaterals， the concept of "new pathogen invading the collaterals" is proposed. Further analysis indicates that this concept aligns with the transmission and pathogenesis patterns of viral respiratory diseases. The treatment method of "clearing epidemic pathogens， detoxifying， and spreading the lung to relieve heat" is considered important for the prevention and control of viral respiratory infectious diseases.
