Analysis of the efficacy of traditional Chinese medicine for diabetic retinopathy based on evidence body quality assessment
- VernacularTitle:基于证据体质量评价的中医药治疗糖尿病视网膜病变效果分析
- Author:
Juan LING
1
,
2
;
Zhuolin XIE
3
;
Xiangxia LUO
3
;
Wanying GUO
1
;
Jiajin LI
1
;
Jun ZHOU
4
;
Xufei LUO
5
Author Information
1. Clinical School of Traditional Chinese Medicine，Gansu University of Chinese Medicine，Lanzhou 730000，China
2. Dept. of Infection Management，Gansu Provincial People’s Hospital，Lanzhou 730000，China
3. Endocrinology Department，Gansu Provincial Hospital of Traditional Chinese Medicine，Lanzhou 730050，China
4. Preventive Treatment Department，Xichang Traditional Chinese Medicine Hospital，Sichuan Xichang 615000，China
5. Evidence-Based Medicine Center，Lanzhou University，Lanzhou 730000，China
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine;
diabetes retinopathy;
meta-analysis;
systematic evaluation;
re-evaluation;
GRADE
- From:
China Pharmacy
2025;36(7):863-866
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the quality of evidence in the systematic evaluation/meta-analysis of traditional Chinese medicine （TCM） for diabetes retinopathy （DR） based on the GRADE system. METHODS Chinese and English databases were searched to obtain the relevant studies of systematic evaluation/meta-analysis of traditional Chinese medicine in the treatment of DR. The search time was from the establishment of each database to January 13th， 2024. According to the inclusion and exclusion criteria， literature screening was conducted. After extracting relevant information from the included literature， the GRADE system was used to evaluate the quality level of the evidence body in the included studies， and the evidence of the outcome indicators was integrated and summarized. RESULTS A total of 51 studies were ultimately included， encompassing 135 outcome indexes. Among these， 19 indicators （14.1%） were of high quality， 87 （64.4%） were of medium quality， 26 （19.3%） were of low quality， and 3 （2.2%） were of very low quality. Overall， the evidence quality of the outcome indicators in the included studies was medium to low quality. The integrated results of evidence on the efficacy of outcome indexes showed that compared with conventional Western medicine， calcium dobesilate or placebo， TCM had significant advantages in improving overall efficacy， reducing bleeding spot area， reducing macular foveal thickness， and increasing visual improvement rate. In addition，the combination of TCM and conventional Western medicine or calcium dobesilate was significantly more effective than using conventional Western medicine or calcium dobesilate alone. CONCLUSIONS The overall quality of the evidence in the systematic evaluation/meta-analysis study on the treatment of DR with TCM is medium to low quality. Based on existing research findings， TCM demonstrates good clinical efficacy in the treatment of DR.
