Muscle myokine irisin: a new target for improving vascular function in hypertension
10.3969/j.issn.1006-2483.2025.02.025
- VernacularTitle:肌肉因子Irisin：改善高血压血管功能的新靶点
- Author:
Jingsui ZHANG
1
,
2
;
Po YANG
3
;
Yueyao ZHANG
2
;
Enpeng HE
2
Author Information
1. Faculty of Geography and Tourism, Xinjiang Normal University , Urumqi , Xinjiang 830054 , China
2. Key Laboratory of Human Body Science , College of Physical Education , Xinjiang Normal University , Urumqi , Xinjiang 830054 , China
3. School of Art and Physical Education , Hebei University of Media and Communication , Shi Jiazhuang , Hebei 051430 , China
- Publication Type:Journal Article
- Keywords:
Irisin;
Hypertension;
Vascular function;
Exercise
- From:
Journal of Public Health and Preventive Medicine
2025;36(2):110-115
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease (CVD) is the most common and fatal non communicable disease in the world. Hypertension accounts for a large proportion of global non communicable diseases. Irisin was first discovered and named in 2012. As a muscle myokine, irisin has the function of regulating glucose and lipid metabolism. Exercise can promote irisin' participation in energy metabolism in the body. At the same time, it has been found that irisin can intervene in the development of hypertension and have a positive effect on the improvement of hypertension. Therefore, this paper reviews research on the relationship between irisin and hypertension, summarizes the mechanism of irisin’ action on vascular function in hypertension, and analyzes the effect of irisin on blood pressure under exercise intervention.
