Detection rate and logistic regression analysis of pulmonary infection in patients with acute exacerbation of chronic obstructive pulmonary disease
10.3969/j.issn.1006-2483.2025.02.010
- VernacularTitle:慢性阻塞性肺疾病急性加重期患者肺部感染检出率及logistic回归分析
- Author:
Yongli XUE
1
;
Juan DU
2
;
Yinzhen SHU
3
;
Lan LIN
4
;
Jun LIU
2
Author Information
1. Department of Internal Medicine,The Second Affiliated Hospital of Chengdu Medical College（China National Nuclear Corporation 416 Hospital）,Chengdu , Sichuan 610051, China
2. Nursing Department,The Second Affiliated Hospital of Chengdu Medical College（China National Nuclear Corporation 416 Hospital）,Chengdu , Sichuan 610051, China
3. Department of Laboratory,The Second Affiliated Hospital of Chengdu Medical College（China National Nuclear Corporation 416 Hospital）,Chengdu , Sichuan 610051, China
4. Department of Surgery,The Second Affiliated Hospital of Chengdu Medical College（China National Nuclear Corporation 416 Hospital）,Chengdu , Sichuan 610051, China
- Publication Type:Journal Article
- Keywords:
Pulmonary infection;
Chronic obstructive pulmonary disease;
Acute exacerbation;
Risk factors
- From:
Journal of Public Health and Preventive Medicine
2025;36(2):43-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the detection rate and risk factors of pulmonary infection in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods A total of 308 patients with AECOPD hospitalized at the Second Affiliated Hospital of Chengdu Medical College were selected from October 2020 to October 2023 as the research subjects. The incidence of pulmonary infections was analyzed, and univariate and logistic multivariate regression analyses were conducted to identify the risk factors of pulmonary infections. Results Among the 308 patients with AECOPD, 155 cases (50.32%) had pulmonary infection and were selected as the infected group, and 153 cases without pulmonary infection were included in the uninfected group. There were no obvious differences in gender, body mass index, education level, drinking history, hypertension, heart failure and malnutrition between the two groups (P>0.05). There were significant differences between the two groups in age, hospitalization time, mechanical ventilation history, smoking history, glucocorticoid use time, and diabetes mellitus (P<0.05). Logistic analysis showed that the ORs of pulmonary infection risk in AECOPD patients with age ≥ 60 years old, hospitalization time ≥ 14 days, mechanical ventilation history, glucocorticoid use time ≥ 7 days, diabetes mellitus, and smoking history were 2.740 (1.024-7.330), 4.586 (2.318-9.071), 3.971 (1.806-8.731), 3.264 (1.419-7.508), 2.680 (1.012-7.100), and 2.826 (1.156-6.909), respectively. Conclusion The risk of pulmonary infection is high in AECOPD patients, which is influenced by factors such as age, hospitalization time, mechanical ventilation history, smoking history, and glucocorticoid use time. Clinical screening should be focused on the above indicators and active prevention and treatment measures should be taken to reduce the occurrence of pulmonary infection.
