Discovery and investigation of six polio vaccine derived viruses in Guangzhou City

Min CUI; Chunhuan ZHANG; Wei ZHANG; Jun LIU; Jialing LI; Jianxiong XU; Wenji WANG; Qing HE; Lihong NI; Xuexia YUN; Huanying ZHENG

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Discovery and investigation of six polio vaccine derived viruses in Guangzhou City

VernacularTitle:广州市6起脊髓灰质炎疫苗衍生病毒的发现与调查
Author: Min CUI ¹ ; Chunhuan ZHANG ¹ ; Wei ZHANG ² ; Jun LIU ² ; Jialing LI ² ; Jianxiong XU ¹ ; Wenji WANG ¹ ; Qing HE ¹ ; Lihong NI ¹ ; Xuexia YUN ¹ ; Huanying ZHENG ²
Author Information

1. Guangzhou Center for Disease Control and Prevention , Guangzhou , Guangdong 510440 , China
2. Guangdong Provincial Center for Disease Control and Prevention , Guangzhou ,Guangdong 511430 , China
Publication Type:Journal Article
Keywords: Polio; Vaccine-derived poliovirus; Investigation and disposal
From: Journal of Public Health and Preventive Medicine 2025;36(2):22-25
CountryChina
Language:Chinese
Abstract: Objective To understand the surveillance situation of poliovirus in Guangzhou from 2011 to 2024, and to further strengthen polio surveillance and ensure the continued maintenance of a polio-free status. Methods An analysis was conducted on the discovery and investigation results of six cases of vaccine-derived poliovirus (VDPV) detected in Guangzhou. Results A total of 6 VDPV incidents were reported in Guangzhou from 2011 to June 2024, among which 5 incidents were from sewage sample testing in the Liede Sewage Treatment Plant in Guangzhou, all of which were confirmed as VDPV, with 1 for type I, 1 for type II, and 3 for type III. In addition, one confirmed HFMD case was identified as a type VDPV II carrier. No presence of any wild poliovirus (WPV), VDPV cases, or circulating VDPV (cVDPV) was reported. Conclusion Guangzhou City has maintained a high level of vigilance and effectiveness in the monitoring and prevention of polio. Continuously strengthening the construction of the polio monitoring network, optimizing vaccination strategies, and comprehensively improving public health awareness are still the focus of the prevention and control work in the future.