Role of Traditional Chinese Medicine in Regulating Immune Inflammation and Microvascular Damage in Preventing Recurrence of Pneumonia During Recovery Based on Combination of Pathogenic Factors
10.13422/j.cnki.syfjx.20250899
- VernacularTitle:基于“因加而发”理论探讨中医药调控免疫炎症微血管损伤在肺炎恢复期“瘥后防复”中的作用
- Author:
Xin PENG
1
;
Haotian XU
1
;
Lei LIANG
1
;
Zheyu LUAN
1
;
Hanxiao WANG
1
;
Kun YANG
1
;
Jihong FENG
2
Author Information
1. Tianjin University of Traditional Chinese Medicine（TCM），Tianjin 301617，China
2. The Second Affiliated Hospital of Tianjin University of TCM，Tianjin 300250，China
- Publication Type:Journal Article
- Keywords:
combination of pathogenic factors;
immune inflammation and microvascular damage;
recovery stage of pneumonia;
prevention of recurrence after recovery;
theoretical discussion
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2025;31(9):249-258
- CountryChina
- Language:Chinese
-
Abstract:
Pneumonia is an infectious disease with high morbidity and mortality worldwide， and its damage to the body is not limited to the acute phase. The theory of combination of pathogenic factors emphasizes that the combination of new pathogens and residual pathogens in the body leads to the occurrence of diseases， which generalizes the causes of recurrence during pneumonia recovery. During the recovery stage of pneumonia， pathological changes such as disturbance of immune homeostasis， persistent low-grade inflammation， and microvascular damage continue to affect the body function， impair the health and quality of life of patients， and increase the risk of secondary infection. According to the theory of traditional Chinese medicine （TCM）， pneumonia is caused by deficiency， and Qi deficiency and blood stasis is the core pathogenesis in the recovery stage. At this time， the body is not full of healthy qi and still has residual pathogens， and thus it is susceptible to external pathogenic factors that lead to disease recurrence. As an important part of the TCM philosophy of treating disease before its onset， prevention of recurrence after recovery emphasizes the need for aftercare in the recovery stage to prevent disease recurrence. Based on the pathogenesis theory of combination of pathogenic factors and the pathogenesis of Qi deficiency and blood stasis， this paper discusses the effect and connotation of TCM in regulating immune inflammation and microvascular damage in preventing recurrence of pneumonia during the recovery stage， aiming to develop new ideas for effective prevention and treatment of pneumonia at this stage.
