Diagnostic and Treatment Approach to Coronary Microvascular Disease from the Perspective of "Disharmony of Blood Collaterals and Dysfunction of Qi Transformation"
10.13288/j.11-2166/r.2025.07.017
- VernacularTitle:从“血络失和、气化失司”探析冠状动脉微血管疾病的辨治
- Author:
Xiaoxiao ZHANG
1
;
Jianguo LIN
1
;
Xiaoning SUN
1
;
Ziyi SUN
1
;
Tong TONG
1
;
Wenqian ZUO
1
;
Zeqi WANG
2
;
Kuiwu YAO
1
Author Information
1. Guang'anmen Hospital，China Academy of Chinese Medical Sciences，Beijing，100053
2. Beijing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
coronary microvascular disease;
disharmony of blood collaterals;
dysfunction of qi transformation;
warming method;
unblocking method;
tonifying method;
activating method
- From:
Journal of Traditional Chinese Medicine
2025;66(7):755-759
- CountryChina
- Language:Chinese
-
Abstract:
The study explores the traditional Chinese medicine （TCM） diagnostic and treatment approach to coronary microvascular disease （CMVD） from the perspective of "disharmony of blood collaterals and dysfunction of qi transformation". It is proposed that the core pathogenesis of CMVD lies in these two mechanisms. From an integrative medicine perspective， different CMVD types are analyzed based on their specific pathogenesis. Through clinical practice， four targeted treatment methods， i.e. warming， unblocking， tonifying， and activating， are formulated. CMVD caused by atherosclerosis is primarily associated with myocardial ischemia， myocardial infarction， and coronary revascularization， with corresponding pathological mechanisms of latent pathogenic obstruction， toxic accumulation in the collaterals， and deficiency with collateral stasis. The disease progression exhibits characteristics of correlation， staging， and transformation. Accordingly， treatment principles include warming to assist qi transformation， unblocking obstruction and dispelling turbidity， activating to disperse toxic stasis and invigorate collaterals， and tonifying to eliminate stasis and nourish collaterals. For CMVD unrelated to atherosclerosis， attention should be paid to the underlying disease， analyzing the main syndromes of blood and collateral disharmony. An approach combining disease-syndrome differentiation with blood and collateral regulation is emphasized for precise treatment.
