Exploring the Traditional Chinese Medicine Diagnosis and Treatment of Psoriasis from the Perspective of Blood Turbidity Theory and Its Correlation with Oxidative Stress
10.13288/j.11-2166/r.2025.07.007
- VernacularTitle:从血浊理论与氧化应激的相关性探讨银屑病的中医辨治
- Author:
Zeju DI
1
;
Suqing YANG
2
;
Qiong ZHANG
2
;
Songyan WANG
2
Author Information
1. Heilongjiang University of Chinese Medicine，Harbin，150040
2. First Affiliated Hospital，Heilongjiang University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
psoriasis;
blood turbidity;
oxidative stress;
angle medicine （角药）
- From:
Journal of Traditional Chinese Medicine
2025;66(7):690-694
- CountryChina
- Language:Chinese
-
Abstract:
Oxidative stress can activate multiple inflammatory pathways， triggering and exacerbating psoriasis lesions. In traditional Chinese medicine （TCM）， blood turbidity refers to a pathological condition in which harmful stimuli or unhealthy lifestyle habits lead to an accumulation of impurities in the blood， resulting in increased viscosity and impaired circulation. Based on the correlation between blood turbidity theory in TCM and the pathological changes of oxidative stress in modern medicine， this paper explored the TCM diagnosis and treatment of psoriasis， proposing that spleen deficiency with latent turbidity is the fundamental cause of the disease. The pathological progression of psoriasis was outlined as follows， spleen deficiency with latent turbidity→phlegm and blood stasis intertwining→internal generation of toxic pathogens. Targeting oxidative stress， the study suggests syndrome differentiation and treatment with angle medicine （角药， means three medicinals combination）. The treatment strategy divided into three stages. For early stage， strengthening the spleen and directing the turbid downward， emphasizing prevention before onset， with angle medicine of Huangqi （Astragali Radix） - Fuling （Poria） - Baizhu （Atractylodis macrocephalae rhizoma） to treat； for middle stage， resolving phlegm and dispersing blood stasis， preventing disease progression， if patient with more phlegm syndrome treated with angle medicine of Banxia （Pinelliae rhizoma） - Chenpi （Citri reticulatae pericarpium） - Zhexie （Alismatis rhizoma）， and if patient with more stasis syndrome treated with Zicao （Arnebiae Radix） - Jixueteng （Spatholobi caulis） - Shouwuteng （Polygonum multiflorum Thunb）； for late stage， resolving toxins and dispelling pathogens， balancing both attack and supplementation， with Quanxie （Scorpio） - Tufuling （Smilacis glabrae rhizoma） - Shudihuang （Rehmanniae radix praeparata） to treat.
