Prevention and Treatment of Cardiovascular-Kidney-Metabolic Syndrome with Traditional Chinese Medicine Based on the Core Pathogenesis Evolution of "Constraint，Heat，Deficiency，Stasis，and Toxin"
10.13288/j.11-2166/r.2025.07.005
- VernacularTitle:从“郁、热、虚、瘀、毒”病机演变探讨心血管-肾脏-代谢综合征的中医药防治
- Author:
Zhichao RUAN
1
;
Jiangteng LIU
1
;
Hua ZHANG
1
;
Weijun HUANG
1
;
Qiang FU
1
;
Shidong WANG
1
;
Jinxi ZHAO
1
Author Information
1. Dongzhimen Hospital，Beijing University of Chinese Medicine，Beijing，100700
- Publication Type:Journal Article
- Keywords:
cardiovascular-kidney-metabolic syndrome;
traditional Chinese medicine theory;
obesity;
diabetes;
chronic kidney disease;
cardiovascular diseases
- From:
Journal of Traditional Chinese Medicine
2025;66(7):680-684
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine （TCM） offers a rich theoretical foundation and clinical experience for the prevention and treatment of cardiovascular-kidney-metabolic syndrome（CKM）， demonstrating unique advantage. Building on previous work in managing diabetes， its complications， and chronic kidney disease， our team has proposed a five-phase evolution theory of "constraint， heat， deficiency， stasis， and toxin" as the core pathogenesis. These phases correspond to the pathological progression of constraint of phlegm-dampness， constraint transforming into heat， heat damaging qi and yin， stasis accumulated in the collateral vessels， and toxin induced by deficiency and stasis. In the prevention and treatment of CKM by TCM， it is emphasized to integrate the concept of "treating disease before it arises" with constitution theory， and incorporate the "2-5-8" prevention and treatment strategy， which combines prevention with treatment， tailors interventions to different phases， and employs comprehensive treatment modalities. Our goal is to leverage TCM's holistic advantages in preventing and treating CKM.
