Research progress of natural bioactive products in resisting loss of skin collagen

VernacularTitle:天然活性成分抑制皮肤胶原蛋白流失的研究进展
Author: Chu-juan HU ; Lu-lu WANG ; Jian-dong JIANG ; Rui LI
Publication Type:Research Article
Keywords: collagen; natural bioactive product; skin aging; mitochondria
From: Acta Pharmaceutica Sinica 2025;60(2):269-279
CountryChina
Language:Chinese
Abstract: As the biggest tissue of human body, skin is the first barrier of resisting external aggression. Collagen is one of important parts of the skin, which could not only affect the aesthetics of skin, but also influence the health and normal function of skin. It is the great significance to find ways that could inhibit the loss of collagen. The mechanisms of the collagen degradation in skin are complex and multifaceted. Natural bioactive products have unique advantages in treating the loss of collagen, which have multi-targets and mechanisms. In this review, the mechanisms of skin collagen degradation are discussed, and the research progress of natural bioactive products in resisting skin aging through promoting collagen synthesis are reviewed, in order to provide references for futural research.