Clinical Analysis of Pituitary Macroadenoma by Transsphenoidal Approach.
- Author:
Jin Han PARK
1
;
Oh Lyong KIM
;
Chan Youl PARK
;
Seong Ho KIM
;
Jang Ho BAE
;
Byung Yon CHOI
;
Soo Ho CHO
Author Information
1. Department of Neurosurgery, School of Medicine, Yeungnam University, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Pituitary macroadenoma;
Transsphenoidal approach;
Nonfunctioning;
Radiotherapy
- MeSH:
Acromegaly;
Catheterization;
Catheters;
Craniotomy;
Headache;
Humans;
Mortality;
Prolactinoma;
Radiotherapy;
Recurrence;
Visual Fields
- From:Journal of Korean Neurosurgical Society
1995;24(12):1530-1536
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The authors report the results of transsphenoidal approach(TSA) for pituitary macroadenoma performd over a 2-year period.This series consisted of 15 patients:ten for nonfunctioning, two for prolactinoma, two of cushing's disease, one of acromegaly. The presenting symptom & sign was hyperfunctioning endocrinopathy in 5 patients, headache in 11 patients, visual symptom in 11 patients. TSA was performed without lumbar catheterization and fluoroscopic mornitoring. Success rates were as follows;normalization of endocrinopathy was achieved in 100% of cases;improvement of visual field in 100% of cases. There were no surgical mortality & some complication with three transient diabetes inspidus one hypopituitarysm. Eight of 15 patients who were removed tumor subtotally were received radiotherapy. Althrough there were short-term follow up(mean 19 months), there was no recurrence. This review reconfirms that the transspenoidal approach is safer and more effective procedure than craniotomy for pituitary macroadenomas.
