Research progress on pathogenesis mechanism of psoriasis and treatment of IL-17 antagonists
10.13200/j.cnki.cjb.004425
- VernacularTitle:银屑病致病机制与白细胞介素-17拮抗剂治疗的研究进展
- Author:
ZHAO Zeyuan
- Publication Type:Journal Article
- Keywords:
Psoriasis;
Animal models;
Interleukin(IL)-17;
Antagonist;
Pharmacodynamics
- From:
Chinese Journal of Biologicals
2025;38(02):221-228+234
- CountryChina
- Language:Chinese
-
Abstract:
Psoriasis is a chronic non-communicable skin disease characterized by red scaly patches on the scalp, knees,elbows, and other areas. It is often accompanied by various diseases such as metabolic arthritis, cardiovascular disease, and depression, which bring a heavy burden to individuals and society. This paper mainly discusses the pathogenesis of psoriasis,the establishment of animal models of psoriasis, the pharmacodynamics evaluation index of psoriasis drugs, and the research progress of current drugs related to interleukin(IL)-17 antagonists, aiming to provide certain references for the development of IL-17-related drugs and the treatment of psoriasis.
