Quality Assessment of Ginger and Its Processed Products Based on Fingerprints and Chemometrics
10.19378/j.issn.1003-9783.2024.10.016
- VernacularTitle:基于指纹图谱和化学计量学的生姜及其炮制品的质量评价
- Author:
Xiujuan YANG
1
,
2
,
3
;
Jianqiao HE
;
Jingjing GUO
;
Jiajia WANG
;
Pengxian NIU
;
Zhijun YANG
;
Yuefeng LI
;
Shou LI
Author Information
1. 甘肃中医药大学,甘肃兰州 730000
2. 西北中藏药省部共建协同创新中心,甘肃兰州 730000
3. 陇药产业创新研究院,甘肃兰州 730000
- Keywords:
Fresh ginger;
dry ginger;
baked ginger;
ginger charcoal;
content determination;
fingerprint;
chemometrics
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2024;35(10):1593-1599
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the fingerprint map and method of multi-component content determination of ginger and its processed products,and to evaluate their quality. Methods High performance liquid chromatography (HPLC) was used to establish the fingerprint of ginger and its processed products (dried ginger,baked ginger,ginger charcoal) and the method for the simultaneous determination of content of five components. The data were analyzed by similarity evaluation and chemical pattern recognition. Results The fingerprint of ginger and its processed products was established. The similarity was ranged from 0.931 to 0.996. A total of 15 common peaks were confirmed. Five components (6-ginger phenol,8-ginger phenol,10-ginger phenol,6-ginger enol,zingiberone) were identified when compared with the standard. The content of 6-ginger phenol,8-ginger phenol and 10-ginger phenol in ginger and its processed products(dried ginger,baked ginger,ginger charcoal),which were determined by HPLC,met the standard of Chinese Pharmacopoeia(2020 edition). The content of 6-ginger enol and zingiberone in fresh ginger was very low,but their content increased significantly after processing into dried ginger and baked ginger. Ginger and its processed products can be divided into different category in cluster analysis. Five components with VIP greater than one were selected by orthogonal partial least squares discriminant analysis. Conclusion The HPLC fingerprint and assay method established in this study are specific,simple and feasible,stable and reliable. With the help of chemical pattern recognition method,it can provide reference for the quality evaluation of ginger and its processed products.
