The application value of SWE in early hepatic fibrosis and renal fibrosis in MAFLD
10.3969/j.issn.1673-9701.2024.33.005
- VernacularTitle:SWE在MAFLD早期肝纤维化及肾纤维化中的应用价值
- Author:
Mengmeng QIAN
1
;
Xiaochen GUO
;
Pengfei WANG
;
Xiu CHEN
;
Xinyao WU
;
Chunpeng ZOU
;
Maosheng XU
Author Information
1. 温州医科大学附属第二医院放射科,浙江温州 325000
- Keywords:
Metabolic associated fatty liver disease;
Shear wave elastography;
Hepatic fibrosis;
Renal fibrosis
- From:
China Modern Doctor
2024;62(33):23-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of shear wave elastography(SWE)in the early assessment of hepatic and renal fibrosis in patients with metabolic associated fatty liver disease(MAFLD).Methods A total of 52 MAFLD patients admitted to the Second Affiliated Hospital of Wenzhou Medical University from July 2023 to May 2024 were selected as MAFLD group,and 40 non-MAFLD patients treated during the same period were served as control group.General information,laboratory data and ultrasound data were collected and compared between two groups.The differences as well as the correlation of the indicators between two groups were compared.The value of SWE in hepatic fibrosis and renal fibrosis in MAFLD patients was assessed.Results Liver function indicators,uric acid and aspartate aminotransferase-to-platelet ratio index(APRI)in MAFLD group were higher than those in control group(P＜0.01);There were no statistically significant differences between two groups in fibrosis 4 index,estimated glomerular filtration rate,serum creatinine and blood urea nitrogen(P＞0.05).The brightness of the liver,liver-kidney ratio,and liver elasticity value were higher in MAFLD group than those in control group(P＜0.05);There was no significant difference in the elasticity value of the right renal cortex between two groups(P＞0.05).Liver elasticity values was positively correlated with alanine aminotransferase(ALT);The liver-kidney ratio was positively correlated with body mass index(BMI),ALT,aspartate aminotransferase,alkaline phosphatase,y-glutamyl transferase and APRI.No significant correlation was found between the right renal cortex elasticity and BMI,estimated glomerular filtration rate,serum creatinine,blood urea nitrogen,or serum uric acid.Conclusion SWE helps in early identification of liver hardness in the MAFLD patients.But the application of SWE in early renal fibrosis in the MAFLD patients needs further evaluation.
