Risk factors of poor prognosis in patients with bloodstream infection caused by extended-spectrum β-lactamase producing enterobacters
10.3969/j.issn.1673-9701.2024.32.010
- VernacularTitle:产超广谱β-内酰胺酶肠杆菌血流感染患者不良预后危险因素分析
- Author:
Yunpeng WANG
1
;
Jijing ZHAO
;
Weixing ZHANG
;
Shu CHEN
;
Fen WU
;
Yumin FU
;
Lizhen ZOU
;
Zhihao ZOU
;
Jialin ZHANG
Author Information
1. 建德市第一人民医院呼吸内科,浙江 杭州 311600
- Keywords:
Extended-spectrum β-lactamase producing enterobacterales;
Bloodstream infection;
Nomogram
- From:
China Modern Doctor
2024;62(32):43-46
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of poor prognosis in patients with extended-spectrum β-lactamase producing enterobacterales(ESBL-E)bloodstream infection,and establish a nomogram prediction model to provide help for clinical diagnosis and treatment.Methods A total of 235 patients with ESBL-E bloodstream infection were collected from the First People's Hospital of Jiande City.According to their prognosis,the patients were divided into survival group(n=211)and death group(n=224).The clinical data of the patients were collected,and the independent risk factors of poor prognosis were screened by multivariate Logistic regression analysis.The nomogram was established and verified.Results The mortality of ESBL-E bloodstream infection patients with shock,respiratory failure,diabetes and leukemia,ICU admission,hypoproteinemia,increased or decreased white blood cells,and thrombocytopenia was higher(P＜0.05).Multivariate Logistic regression analysis showed that combined shock,respiratory failure and leukemia were independent risk factors for death from ESBL-E bloodstream infection.Conclusion The nomogram prediction model of adverse prognostic risk factors in patients with ESBL-E bloodstream infection can provide help for clinicians to judge the poor prognosis in the early stage,and it is of reference significance to take early intervention measures to reduce the mortality of patients.
