Study on the prediction of acute coronary syndrome based on coronary fat attenuation index and laboratory indicators
10.3969/j.issn.1673-9701.2024.32.003
- VernacularTitle:冠状动脉周围脂肪衰减指数联合实验室指标预测急性冠脉综合征的研究
- Author:
Lin YANG
1
;
Weitao YE
;
Shaorong WANG
;
Lusi WU
;
Jun YANG
;
Ximing CAO
Author Information
1. 南方医科大学附属广东省人民医院(广东省医学科学院)放射科,广东 广州 510080
- Keywords:
Coronary computed tomography angiography;
Coronary heart disease;
Acute coronary syndrome;
Fat attenuation index
- From:
China Modern Doctor
2024;62(32):11-15
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of coronary fat attenuation index(FAI)combined with laboratory indicators in predicting the risk of acute coronary syndrome(ACS)in patients with coronary heart disease(CHD).Methods A retrospective analysis was conducted on 454 patients who were diagnosed with CHD in Guangdong Provincial People's Hospital SCAD group(n=233)and an ACS group(n=221).Univariate and multivariate Logistic regression analyses were performed on the FAI values of the main coronary branches[right coronary artery(RCA),left anterior descending branch(LAD),left circumflex branch(LCX)],laboratory indicators,and clinical data,to identify independent risk factors for ACS in CHD patients.Receiver operating characteristic curves were constructed,and area under the curve(AUC)was calculated to evaluate the predictive performance of the independent risk factors and their combinations.Results LAD-FAI,RCA-FAI,and high-sensitivity C-reactive protein(hs-CRP)were independent influencing factors for ACS in CHD patients.The AUC for the prediction of ACS occurrence in CHD patients based on LAD-FAI,RCA-FAI,and elevated hs-CRP values alone were 0.568,0.703,and 0.749,respectively.When these three factors were analyzed in combination,the AUC was 0.815.Conclusion The combined analysis of LAD-FAI,RCA-FAI,and hs-CRP has good predictive performance for assessing the risk of ACS in CHD patients.
