Influencing factors of mycoplasmal pneumonia complicated with pleural effusion in children
10.3969/j.issn.1673-9701.2024.31.011
- VernacularTitle:小儿支原体肺炎合并胸腔积液的影响因素探究
- Author:
Danyang WANG
1
;
Yan CHEN
Author Information
1. 金华市人民医院儿科,浙江金华 321000
- Keywords:
Mycoplasmal pneumonia;
Pleural effusion;
Influencing factor;
Diagnostic value
- From:
China Modern Doctor
2024;62(31):47-50,75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors of mycoplasmal pneumonia(MPP)with pleural effusion in children.Methods A total of 168 children with MPP admitted to Jinhua People's Hospital from January 2021 to November 2023 were selected and divided into non-pleural effusion group(115 cases)and pleural effusion group(53 cases)according to imaging results.Basic information,laboratory indicators and chest imaging results were collected.Multivariate Logistic regression analysis was used to explore the influencing factors of pleural effusion in MPP children.Receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic efficiency of laboratory indicators.Results The platelet count,interleukin(IL)-10 and IL-4 of children in pleural effusion group were significantly lower than those in non-pleural effusion group,C-reactive protein(CRP),procalcitonin,lactate dehydrogenase,D-dimer,glycosaminoglycan(GAG),IL-17 and interferon-γ(IFN-γ)were significantly higher than those in non-pleural effusion group(P＜0.05).Multivariate Logistic regression analysis showed that CRP,lactate dehydrogenase,D-dimer,GAG,IL-17,IL-4 and IFN-γ were independent influencing factors of pleural effusion in MPP children(P＜0.05).ROC curve analysis results showed that the areas under the curve of GAG,IFN-γ,D-dimer,CRP,IL-4,lactate dehydrogenase and IL-17 predicting pleural effusion in MPP children were 0.954,0.824,0.813,0.786,0.765,0.732 and 0.727,respectively.The sensitivity(96.4％),specificity(93.1％)and accuracy(95.4％)of serum GAG were the highest.Conclusion Serum CRP,lactate dehydrogenase,D-dimer,GAG,IL-17,IL-4 and IFN-γ are all independent influencing factors for pleural effusion in MPP children,and have certain diagnostic value for pleural effusion in MPP children.
