The diagnostic value of deep medullary vein score for cognitive impairment in cerebral small vessel disease
10.3969/j.issn.1673-9701.2024.30.007
- VernacularTitle:深髓静脉评分对脑小血管病患者认知功能障碍的诊断价值
- Author:
Qingchun WANG
1
;
Shida XU
;
Haiyuan LAN
;
Xinjun LEI
Author Information
1. 浙江中医药大学附属丽水中医院放射科,浙江丽水 323000
- Keywords:
Deep medullary vein;
Cognitive impairment;
Cerebral small vessel disease;
Magnetic resonance imaging
- From:
China Modern Doctor
2024;62(30):37-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of deep medullary vein (DMV) score for cognitive impairment in patients with cerebral small vessel disease (CSVD).Methods Collect clinical and imaging data of 108 patients who visited Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University from May 2022 to December 2023.According to the mini-mental state examination,patients were divided into a cognitive impairment group (36 cases) and a cognitive function normal group (72 cases).On magnetic sensitive images,the DMV scores of the six regions on both sides of the frontal lobe,parietal lobe,occipital lobe are rated from 0 to 3 points based on their visual conditions,and the total scores of the six regions is the DMV score (0 to 18 points).Applying international CSVD guidelines to assess CSVD burden in patients.Analyze the correlation between DMV score and cognitive impairment,and compare the diagnostic value of DMV scores and CSVD score for cognitive impairment.Results The median CSVD burden score of 108 patients was 1 (0,2) points,and the median DMV score was 4 (1,9) points.The DMV score was positively correlated with the presence of cognitive impairment (r=0.525,P<0.001).There were statistically significant differences in age,cerebral microbleeds,perivascular space enlargement,white matter hyperintensities,CSVD burden,and DMV score between the cognitive impairment group and the cognitive function normal group (P<0.05).The area under the receiver operating characteristic curve of diagnosed with cognitive impairment using DMV score was 0.820 (95％CI:0.741-0.898,P<0.001).Conclusion DMV score is positively correlated with CSVD cognitive impairment,and it has certain predictive value for cognitive impairment.
