Analysis of quality of life and influencing factors in patients with multidrug-resistant tuberculosis
10.3969/j.issn.1673-9701.2024.29.003
- VernacularTitle:耐多药肺结核病患者生命质量及影响因素分析
- Author:
Yajun SHI
1
;
Xiaoqin XIONG
;
Xiaoqing FU
;
Feng WANG
;
Hui ZHOU
Author Information
1. 巴中市中心医院感染疾病科,四川巴中 636000
- Keywords:
Drug-resistant pulmonary tuberculosis;
Health;
Quality of life;
Influencing factors
- From:
China Modern Doctor
2024;62(29):10-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the health-related quality of life(HRQOL)among patients with multidrug-resistant and rifampin-resistant pulmonary tuberculosis(MDR/RR-PTB)and analyze its influencing factors.Methods Data was collected from 50 MDR/RR-PTB patients registered for treatment management in the"Tuberculosis Management Information System"in Bazhong City from 2021 to 2024 as resistance group.Fifty pulmonary tuberculosis patients sensitive to anti-tuberculosis drug treatment registered in the system during the same period were selected as control group.A cross-sectional survey method was employed using the quality of life instruments for chronic disease pulmonary tuberculosis(QLICD-PT)to measure and compare the HRQOL between two groups.Multiple linear regression analysis was used to analyze factors affecting the HRQOL of MDR/RR-PTB patients.Results Except for physiological function,there were statistically significant difference between MDR/RR-PTB group and control group in terms of total quality of life score,psychological function,social function,and specific modules(P＜0.05).Univariate analysis showed that there were statistically significant differences in the total quality of life scores among patients with different genders,medical insurance statuses,monthly family income situations,presence or absence of comorbidities,lymphocyte count,albumin,C-reactive protein,and body mass index(P＜0.05).Multiple linear regression analysis revealed that(P＜0.05)there was significant difference for the partial regression coefficient tests of patient's medical insurance and monthly family income situations(P＜0.05).Conclusion The HRQOL of MDR/RR-PTB patients is lower than that of pulmonary tuberculosis patients sensitive to anti-tuberculosis drugs.The patient's health insurance and monthly family income are potential factors affecting the HRQOL of MDR/RR-PTB patients.
