Efficacy analysis of Jiawei Sangju decoction combined with oseltamivir in the treatment of influenza B complicated with benign acute childhood myositis
10.3969/j.issn.1673-9701.2024.22.023
- VernacularTitle:加味桑菊饮联合奥司他韦治疗乙型流感并发儿童急性良性肌炎的疗效分析
- Author:
Feifei WANG
1
;
Xiaobin DOU
;
Chaoli CAI
;
Chaoxiong WU
;
Jiajia WANG
;
Weijian XI
Author Information
1. 温州市中西医结合医院儿科,浙江温州 325000
- Keywords:
Influenza B;
Benign acute childhood myositis;
Jiawei Sangju decoction;
Oseltamivir
- From:
China Modern Doctor
2024;62(22):96-100
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore clinical effect of Jiawei Sangju decoction combined with oseltamivir in the treatment of influenza B complicated with benign acute childhood myositis(BACM).Methods Sixty children with influenza B complicated with BACM hospitalized in the Department of Pediatrics,Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine from January 2021 to January 2024 were selected and divided into control group and study group according to random number table method,with 30 cases in each group.The control group was treated with oseltamivir,and the study group was treated with Jiawei Sangju decoction combined with oseltamivir.The clinical efficacy,symptom improvement time and aspartate transaminase(AST),alanine transaminase(ALT),creatine kinase(CK),creatine kinase isozyme(CK-MB),lactate dehydrogenase(LDH)and myoglobin(Mb)before and after treatment were compared between two groups.Results After treatment,the total effective rate of study group was significantly higher than that of control group(χ2=5.455,P=0.020).The duration of fever and leg pain relief in study group were significantly shorter than those in control group(P<0.05).After 5 days of treatment,the levels of AST,CK,CK-MB,LDH and Mb in two groups were significantly lower than before treatment(P<0.05),and the levels of AST,CK,CK-MB,LDH and Mb in study group were significantly lower than those in control group(P<0.05).Conclusion Jiawei Sangju decoction combined with oseltamivir can improve the symptoms of influenza B with BACM,reduce the levels of muscle enzyme and Mb,and have a positive effect on the prognosis of children.
