Clinical efficacy study of fluoxetine hydrochloride capsules and escitalopram oxalate tablets in the treatment of first-episode depression disorder
10.3969/j.issn.1673-9701.2024.21.024
- VernacularTitle:盐酸氟西汀胶囊和草酸艾司西酞普兰片治疗首发抑郁症的临床效果研究
- Author:
Zengming MA
1
;
Jindong CHEN
;
Yuping XIA
;
Xiaoqian WEI
;
Chuan'an ZHU
;
Zhiyuan HUANG
Author Information
1. 厦门市仙岳医院厦门医学院附属仙岳医院福建省精神医学中心福建省精神疾病临床医学研究中心住院部,福建厦门 361012
- Keywords:
First-episode depression disorder;
Escitalopram oxalate tablets;
Fluoxetine hydrochloride capsules;
Clinical efficacy
- From:
China Modern Doctor
2024;62(21):108-110,121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficacy of fluoxetine hydrochloride capsules and escitalopram oxalate tablets in the treatment of first-episode depression disorder.Methods Eighty patients with first-episode depression disorder who were hospitalized in the 14th district of Integrated Traditional Chinese and Western Medicine of Xiamen Xianyue Hospital from February to November 2023 were selected,and divided into fluoxetine hydrochloride capsules group(n=40)and escitalopram oxalate tablets group(n=40)according to random number method;Conducted the Hamilton depression scale(HAMD)estimates before treatment and four weeks after treatment,to analyze and compare the clinical efficacy of two groups.Results After four weeks of treatment,the HAMD scores of all patients significantly decreased compared to before treatment in this group(P＜0.01);There was no statistically significant difference between two groups(P＞0.05).There was no statistically significant difference in the total effective rate between two groups(P＞0.05).Conclusion Escitalopram oxalate tablets and fluoxetine hydrochloride capsules were both effective in treatment of the first-episode depression disorder patients,and the total effective rates of them were similar.
