Clinical observation of Zishen Yutai pill combined with beimiheparin sodium in recurrent spontaneous abortion of kidney deficiency and blood stasis type
10.3969/j.issn.1673-9701.2024.21.023
- VernacularTitle:滋肾育胎丸联合贝米肝素钠治疗肾虚血瘀型复发性流产的临床观察
- Author:
Chen GUO
1
;
Yunhui WAN
;
Yingchun YI
;
Xiaoling ZHANG
Author Information
1. 江西省妇幼保健院生殖健康科,江西南昌 330006
- Keywords:
Recurrent spontaneous abortion;
Zishen Yutai pill;
Beimiheparin sodium;
Sex hormone levels;
Traditional Chinese medicine syndrome score
- From:
China Modern Doctor
2024;62(21):104-107
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effect of Zishen Yutai pill combined with beimiheparin sodium in the treatment of recurrent spontaneous abortion(RSA)of kidney deficiency and blood stasis type.Methods A total of 98 RSA patients with kidney deficiency and blood stasis type admitted to Jiangxi Maternal and Child Health Hospital from January 2021 to June 2023 were randomly divided into observation group and control group,49 cases in each group.The patients of control group were treated with beimiheparin sodium,while the patients of observation group were treated with Zishen Yutai pill.Compare the clinical efficacy,traditional Chinese medicine syndrome score,sex hormone levels,uterine artery blood flow parameters,fetal protection status,and adverse reactions between two groups.Results After treatment,the total effective rate of observation group was higher than that of control group(P＜0.05);Observation group had lower rates of repeated pregnancies,falls,lumbosacral pain,vaginal bleeding,and knee soreness and softness scores than control group(P＜0.05);The levels of progesterone,human chorionic gonadotropin,and estradiol in observation group were higher than those in control group(P＜0.05);The uterine artery resistance index,systolic and diastolic flow velocity ratio,and pulse index in observation group were lower than those in control group(P＜0.05);The success rate and live birth rate of observation group were higher than those of control group(P＜0.05);There was no statistically significant difference in the adverse reactions between two groups of patients(P＞0.05).Conclusion The combination of Zishen Yutai pill and beimiheparin sodium can improve the therapeutic effect of RSA patients,improve their sex hormone levels,facilitate fetal preservation,and increase the final live birth rate.
