A single-center retrospective study of clinical characteristics in elderly patients with acute pancreatitis
10.3969/j.issn.1673-9701.2024.19.018
- VernacularTitle:老年急性胰腺炎患者临床特征的单中心回顾性研究
- Author:
Pengfei ZHANG
1
;
Chunxiang WANG
;
Fengjuan JIANG
Author Information
1. 扬州大学附属江都人民医院消化内科,江苏扬州 225000
- Keywords:
Acute pancreatitis;
Elderly;
Death;
Intensive care unit;
Hospital stay
- From:
China Modern Doctor
2024;62(19):84-88
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics of elderly patients with acute pancreatitis(AP),and to provide a basis for the prevention and treatment of elderly patients with AP.Methods Clinical data of AP patients treated in Jiangdu People's Hospital Affiliated to Yangzhou University from March 2021 to March 2023 were collected and divided into elderly group(≥65 years old,167 cases)and non-elderly group(＜65 years old,303 cases)according to age.The clinical characteristics,biochemical indexes,mortality,intensive care unit(ICU)hospitalization rate,length of stay,Ranson score,Charlson comorbidity index(CCI)and so on were compared between the two groups.Results The age of elderly group was significantly higher than that of non-elderly group,lactate dehydrogenase,aspartate aminotransferase,serum amylase,Ranson score,the proportion of cardiovascular complications,pulmonary complications,nervous system complications,CCI ≥ 2 and the incidence of jaundice were significantly higher than those of non-elderly group(P＜0.05).The mortality rate and ICU hospitalization rate of elderly group were significantly higher than that of non-elderly group,and the hospital stay was significantly longer than that of non-elderly group(P＜0.05).Multivariate analysis showed that age ≥65 years,Ranson score ≥3,CCI≥ 2 and pancreatic necrosis were independent risk factors for death and ICU admission in AP patients(P＜0.05),age ≥65 years,pancreatic necrosis,and biliary causes were independent risk factors for prolonged hospital stay(P＜0.05).Conclusion Compared with middle-aged and young patients,elderly AP patients have higher mortality,higher ICU hospitalization rate and longer hospital stay.Early identification and timely treatment are key factors to improve prognosis elderly AP patients.
