The preventive effect of sodium hyaluronate-carboxymethyl cellulose anti-adhesion film and IUD on readhesion in TCRA
10.3969/j.issn.1673-9701.2024.18.013
- VernacularTitle:TCRA术中应用透明质酸钠-羧甲基纤维素防粘连膜与宫内节育器对再粘连的预防效果
- Author:
Ying LYU
1
;
Mengya YU
;
Qiong XIA
Author Information
1. 湖南省妇幼保健院宫内疾病与介入治疗专科,湖南长沙 410000
- Keywords:
Sodium hyaluronate-carboxymethyl cellulose anti-adhesion film;
Intrauterine device;
Electrohysterectomy adhesions;
Readhesion
- From:
China Modern Doctor
2024;62(18):58-61,72
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the preventive effect of sodium hyaluronate-carboxymethyl cellulose anti-adhesion membrane plus intrauterine device(IUD)on readhesion in transcervical resection of adhesion(TCRA).Methods A total of 89 patients with moderate to severe intrauterine adhesions who received TCRA treatment in Hunan Maternal and Child Health Hospital from February 2021 to February 2022 were selected,patients were divided into control group(n=44)and study group(n=45)using the envelope method.Patients in control group were placed with IUD;Patients in study group were treated with sodium hyaluronate carboxymethyl cellulose anti adhesion film in addition to control group.The intrauterine adhesion,curative effect,menstrual recovery and American Fertility Association(AFS)scoring were compared between the two groups,and the pregnancy status of the patients within one year of follow-up was recorded.Results Compared with control group,the incidence of readhesion in study group patients decreased(P<0.05);The good rate of postoperative menstrual recovery was higher than that of control group(P<0.05);The total effective rate of treatment was higher than that of control group(P<0.05);The AFS scoring of study group patients were lower than those of control group in terms of adhesion range,adhesion type,menstrual pattern score,and total score(P<0.05).There was no statistically significant difference in clinical pregnancy rate between the two groups(P>0.05).Conclusion In TCRA,the combination of sodium hyaluronate-carboxymethyl cellulose anti-adhesion membrane and IUD can significantly reduce the incidence of readhesion,improve the postoperative good rate of menstrual recovery and the overall treatment response rate,the clinical pregnancy rate was not affected.
