Evaluation of the accuracy and reliability of tear film rupture time measurement in the diagnosis of dry eye in adolescents
10.3969/j.issn.1673-9701.2024.17.013
- VernacularTitle:泪膜破裂时间测定在青少年干眼症诊断中的准确性和可靠性评价
- Author:
Ziya LIU
1
;
Congcong JIANG
Author Information
1. 温州市中西医结合医院眼科,浙江温州 325000
- Keywords:
Tear film rupture time;
Teenagers;
Dry eye diagnosis;
Accuracy;
Reliability
- From:
China Modern Doctor
2024;62(17):54-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy and reliability of tear film rupture time(TBUT)measurement in the diagnosis of dry eye in adolescents.Methods A total of 185 adolescents with dry eye treated in our hospital from September 2021 to September 2023 were selected as the observation group,and 20 healthy adolescents were selected as the control group.The accuracy and reliability evaluation of TBUT measurement in the diagnosis of dry eye in adolescents were analyzed.Results Among 185 patients,invasive TBUT detection detected 132 cases,the total detection rate was 71.35% ,non-invasive TBUT detection detected 160 cases,the total detection rate was 84.49% ,there was a statistical difference between groups(P＜0.05).Among the 185 patients,there were 128 cases of non-meibomian gland dysfunction and 57 cases of meibomian gland dysfunction.The detection rate of non-meibomian gland dysfunction by invasive TBUT detection was 41.62% ,and the detection rate of meibomian gland dysfunction was 29.73% ,and the detection rate of non-invasive TBUT detection was 63.24% ,and the detection rate of meibomian gland dysfunction was 23.24% .There was statistical difference between groups(P＜0.05).Compared with control group,TBUT,initial TBUT and average TBUT in observation group were significantly decreased(P＜0.05).Compared with group A,TBUT,first time TBUT and average TBUT in group B were significantly decreased,with statistical difference between groups(P＜0.05).The sensitivity,specificity and AUC of invasive TBUT detection were 72.49% ,75.88% and 0.762,and the sensitivity,specificity and area under the curve(AUC)of non-invasive TBUT detection were 87.24% ,90.05% and 0.926.Conclusion TBUT has diagnostic value in the diagnosis of juvenile dry eye,and compared with invasive TBUT,non-invasive TBUT is more accurate and reliable.
