Observation of clinical efficacy and laboratory indexes of traditional Chinese medicine in treating patients with AECOPD
10.3969/j.issn.1673-9701.2024.16.020
- VernacularTitle:中药协定方治疗AECOPD患者的临床疗效及实验室指标观察
- Author:
Qiang XIAO
1
;
Wenming SONG
;
Mu MEI
;
Susu DONG
;
Yafen TAN
;
Xuan ZHANG
;
Lu YAO
;
Tianli WANG
Author Information
1. 常德市第一人民医院呼吸与危重症医学科,湖南常德 415003
- Keywords:
Traditional Chinese medicine turbid phlegm obstructing lung decoction;
Acute exacerbation of chronic obstructive pulmonary disease;
Traditional Chinese medicine therapy
- From:
China Modern Doctor
2024;62(16):85-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of traditional Chinese medicine turbid phlegm obstructing lung decoction on patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)and its influence on laboratory indexes.Methods A total of 191 patients with AECOPD who were hospitalized in the First People's Hospital of Changde from January 2021 to December 2022 were selected.Patients were divided into observation group(96 cases)and control group(95 cases)according to their treatment intention.The control group received conventional treatment of western medicine,and the observation group received oral administration of traditional Chinese medicine turbid phlegm obstructing lung decoction for one week.TCM symptom scores,COPD assessment test(CAT),lung function,laboratory indicators and efficacy were compared between two groups.Results The total effective rate of observation group was significantly higher than that of control group(χ2=4.573,P=0.030).After treatment,TCM symptom score,CAT score,hypersensitive C-reaction protein(hsCRP)and interleukin-6(IL-6)of patients in both groups were significantly lower than before treatment,percentage of forced vital capacity to predicted value(FVC%)and percentage of forced expiratory volume in one second to predicted value(FEV1%)were significantly higher than before treatment(P<0.05),arterial partial pressure of carbon dioxide(PaCO2)of observation group was lower than before treatment,and arterial partial pressure of oxygen(PaO2)was higher than before treatment(P<0.05).The TCM symptom score,CAT score,hsCRP and IL-6 of observation group were significantly lower than those of control group,while FVC%,FEV1%and PaO2 were significantly higher than those of control group(P<0.05).Conclusion On the basis of western medicine treatment,traditional Chinese medicine turbid phlegm obstructing lung decoction can more effectively improve clinical symptoms of AECOPD patients,relieve the inflammation in the body,contribute to the recovery of lung function and improve the quality of life of patients.
