Correlation study between cerebral microbleeds and cognitive dysfunction in patients with cerebral small vessel disease
10.3969/j.issn.1673-9701.2024.15.011
- VernacularTitle:脑微出血与脑小血管病患者认知功能障碍的相关性研究
- Author:
Jianguo ZHOU
1
;
Dayong FU
;
Yundan WANG
;
Xianjun MA
Author Information
1. 南京中医药大学连云港附属医院放射科,江苏连云港 222004
- Keywords:
Cerebral microbleeds;
Cerebral small vessel disease;
Montreal cognitive assessment scale;
Susceptibility weighted
- From:
China Modern Doctor
2024;62(15):51-53,66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore correlation between cerebral microbleeds(CMBs)and cognitive dysfunction in patients with cerebral small vessel disease.Methods A total of 80 patients with cerebral small vessel disease admitted to Department of Encephalopathy in Nanjing University of Chinese Medicine Affiliated Lianyungang Hospital from January 2020 to December 2022 were selected as research objects.They were divided into CMBs positive group(50 cases)and CMBs negative group(30 cases)based on the presence or absence of CMBs in the cerebral hemisphere.General clinical data of two groups were compared.Cognitive function was assessed by using Montreal cognitive assessment scale(MoCA).Results Age and incidence rate of hypertension in CMBs positive group were significantly higher than those in CMBs negative group(P<0.05).Total score of MoCA,scores of visuospatial and executive function,abstract thinking and delayed recall in CMBs positive group were significantly lower than those in CMBs negative group(P<0.05).Conclusion CMBs are closely related to the potential mechanism,clinical diagnosis and degree assessment of cognitive dysfunction in patients with cerebral small vessel disease.
